Abou Dao
Hôpital de District de Bogodogo, Burkina Faso
Title: Neurocysticercosis discovered incidentally during an asynchronous single brain metastasis of breast adenocarcinoma
Biography
Biography: Abou Dao
Abstract
Background: Neurocysticercosis is anthropozoonosis of the central nervous system. We report a case of an asynchronous single brain metastasis of breast adenocarcinoma.
Clinical Observation: In 2011, we received Mrs M P L, 37 years old, who had a left breast adenocarcinoma, classified as T4bN1M0, positive for hormonal receptors and HER2+++ for whom she received neoadjuvant chemotherapy and then a patey. Histopathology concluded a residual adenocarcinoma classified TBNA of Sataloff. 50Gy radiotherapy was administered on the wall followed by tamoxifen prescribed for 5 years. The patient, considered in complete remission, was followed. Twenty months after chemotherapy, she was admitted to rebel headaches and vertigo. The examination found a patient with 80% Karnofsky index, apyretic with a separation of the levitation polygon. Cerebral MRI revealed a single 32x30 mm left temporo-occipital lesion with peri-lesional infiltration. CA15.3 was high at 159.8 IU/ml. No other metastasis has been revealed. A stereotaxic biopsy was performed and histopathology concluded a breast adenocarcinoma, CK7 positive, Her2 negative, hormonal receptors positive and discovery of a live cysticercus larva. Management consisted of corticosteroid therapy, albendazole and brain radiotherapy in toto, followed by boosting the lesion. The evolution was marked a clear clinical and radiological improvement. CA15.3 control was normal. Unfortunately, patients die one year after the brain radiotherapy.
Conclusion: The association of a neurocysticercosis with an adenocarcinoma is possible especially in tropical zone patients. Concurrent management could improve local control but survival remains short.