Neuromuscular Disease

Neuromuscular Disorders is a term that encompasses many diseases and ailments that impairs with the functioning of muscles. It affects the peripheral nervous system, which consists of all the motor and sensory nerves that connect the brain and spinal cord to the rest of the body.  Dynamic muscle weakness is the predominant state of these disorders.

Example of NMD includes:

  • Amyotrophic lateral sclerosis
  • Multiple sclerosis
  • Myasthenia gravis
  • Spinal muscular atrophy

 

Myasthenia Gravis is an autoimmune disease that affects the neuromuscular junction. With a prevalence of 150-250 cases per 1 million, MG and its subgroups are the major disorders that affect neuromuscular junction.

Multiple Sclerosis is an inherited disorder.  According to the estimation of Multiple Sclerosis Foundation, about 2.5 MN people around the world have MS. The ration of men with MS to women with the disease is 1 to 2. Amyotrophic lateral sclerosis is a progressive neurological disorder that affects the function of nerves and muscles. According to an estimation ALS is the cause of five in every 100, 000 deaths in people ages 20 or older

Spinal Muscular Atrophy is a fatal autosomal recessive disorder which affects 1 in 40 people that carries SMA gene. It causes progressive muscle wasting and paralysis. 

  • Multiple sclerosis
  • Myasthenia gravis
  • Hyper reflexia
  • Spine muscular atropies
  • Spasticy
  • Neuromuscular junction disorder
  • Muscular dystrophy
  • Amyotrophic lateral sclerosis
  • Spinal muscular atrophy
  • Anterior,Central & Posterior Cord syndrome
  • Care Practice and Awareness
  • Therapeutic Targets & Mechanisms for Treatment

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